CD170 (clone 3F5A3), anti-human

CD170 (clone 3F5A3), anti-human

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In stock
SKU
BT-MCA4028
Catalog Number: BT-MCA4028
Size(s): 50μL, 100μL
Isotype: Mouse IgG2a
Reactivity: human
Application(s): FCM
Datasheet
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Background:
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Research Area: Others

Synonyms: SIGLEC5, OBBP2, CD33L2, OB-BP2, SIGLEC-5

Immunogen: Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage
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