CD18 (LTBR) polyclonal, anti-human

Quantity: 100 µg

Background:
LTBR(Lymphotoxin B Receptor), also called TNFCR or LT-BETA-R, is a receptor for lymphotoxin which in humans is encoded by the LTBR gene. By linkage analysis with recombinant inbred mouse strains, Nakamura et al.(1995) demonstrated that the Tnfcr locus is close to the Tnfr1 gene on mouse chromosome 6. Presumably, the human homolog is located on 12p13. Silva-Santos et al.(2005) reported that double-positive T cells regulate the differentiation of early thymocyte progenitors and gamma-delta cells by a mechanism dependent on the transcription factor ROR-gamma-t and the lymphotoxin-beta receptor. Lo et al.(2007) identified lymphotoxin and LIGHT(TNFSF14), tumor necrosis factor cytokine family members that are primarily expressed on lymphocytes, as critical regulators of key enzymes that control lipid metabolism.

Description:
Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 3 (LTBR) detection. Tested with WB, IHC-P in Human.

Synonyms:
CD 18 antibody, CD18 antibody, CD18 antigen antibody, D12S370 antibody, LT beta R antibody, LTBETAR antibody, Ltbr antibody, Lymphotoxin B receptor antibody, Lymphotoxin beta receptor(TNFR superfamily, member 3) antibody, Lymphotoxin beta receptor antibody, Lymphotoxin-beta receptor antibody, TNF R III antibody, TNF-RIII antibody, TNFCR antibody, TNFR RP antibody, TNFR superfamily member 3 antibody, TNFR-III antibody, TNFR2 RP antibody, TNFR2RP antibody, TNFR3 antibody, TNFRII antibody, TNFRRP antibody, TNFRSF 3 antibody, TNFRSF3 antibody, TNR3_HUMAN antibody, Tumor necrosis factor C receptor antibody, Tumor necrosis factor receptor 2 related protein antibody, Tumor necrosis factor receptor 2-related protein antibody, Tumor necrosis factor receptor superfamily member 3 antibody, Tumor necrosis factor receptor superfamily member 3 precursor antibody, Tumor necrosis factor receptor type III antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human LTBR(420-435aa ATPSNRGPRNQFITHD).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.