CD18 monoclonal antibody, anti-human, mouse

Background:
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

Research Area: Immunology, Signal transduction, Stem cells

Synonyms: ITGB2, CD18, MFI7, Integrin beta-2, Cell surface adhesion glycoproteins LFA-1, CR3, p150, 95 subunit beta, Complement receptor C3 subunit beta, CD antigen CD18

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year