CD18 Polyclonal Antibody

Background:
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Immunology, Signal Transduction, Stem Cells

Synonyms:
CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, ITGB2

Immunogen: A synthetic peptide of human CD18 (NP_000202.3).

Swissprot: P05107
Gene ID: 3689

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.