CD181 (CXCR1) polyclonal, anti-human

Quantity: 100 µg

Background:
CXCR1(Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al.(1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al.(2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA(GRO) with a low affinity.

Description:
Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 1 (CXCR1) detection. Tested with WB, IHC-P in Human.

Synonyms:
C C antibody, C C CKR 1 antibody, C-X-C chemokine receptor type 1 antibody, CCCKR1 antibody, CD 181 antibody, CD128 antibody, CD181 antibody, CD181 antigen antibody, CDw128a antibody, Chemokine(C X C motif) receptor 1 antibody, Chemokine(C X C) receptor 1 antibody, Chemokine receptor 1 antibody, CKR 1 antibody, CMKAR1 antibody, CXC-R1 antibody, CXCR 1 antibody, CXCR-1 antibody, CXCR1 antibody, CXCR1_HUMAN antibody, High affinity interleukin 8 receptor A antibody, High affinity interleukin-8 receptor A antibody, IL 8 receptor type 1 antibody, IL 8R A antibody, IL-8 receptor type 1 antibody, IL-8R A antibody, IL8 receptor antibody, IL8 receptor type 1 antibody, IL8R1 antibody, IL8RA antibody, IL8RBA antibody, Interleukin 8 receptor alpha antibody, Interleukin 8 receptor type 1 antibody, Interleukin 8 receptor type A antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR1(24-38aa DEDYSPCMLETETLN).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.