CD185 (CXCR5) polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CXCR5(Chemokine CXC Motif Receptor 5), also known as BLR1, is a G protein-coupled seven transmembrane receptor for chemokine CXCL13(also known as BLC) and belongs to the CXC chemokine receptor family. In humans, the CXC-R5 protein is encoded by the CXCR5 gene. The gene plays an essential role in B cell migration. Reif et al.(2002) concluded that their findings defined the mechanism of B-cell relocalization in response to antigen, and established that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones. Chan et al.(2003) investigated the expression of chemokines and chemokine receptors in eyes with primary intraocular B-cell lymphoma(PIOL).

Description:
Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 5 (CXCR5) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
BLR 1 antibody, BLR1 antibody, Burkitt lymphoma receptor 1 antibody, Burkitt lymphoma receptor 1 GTP binding protein antibody, C X C chemokine receptor type 5 antibody, C-X-C chemokine receptor type 5 antibody, CD 185 antibody, CD185 antibody, CD185 antigen antibody, Chemokine C X C motif receptor 5 antibody, Chemokine CXC motif receptor 5 antibody, Chemokine receptor 5 antibody, CXC chemokine receptor type 5 antibody, CXC R5 antibody, CXC-R5 antibody, CXCR 5 antibody, CXCR-5 antibody, Cxcr5 antibody, CXCR5_HUMAN antibody, MDR 15 antibody, MDR-15 antibody, MDR15 antibody, MGC117347 antibody, Monocyte derived receptor 15 antibody, Monocyte-derived receptor 15 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human CXCR5(358-372aa SSLSESENATSLTTF), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human CXCR5(358-372aa SSLSESENATSLTTF), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.