CD186 (Bonzo) polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
CXCR6(Chemokine,CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al.(1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al.(2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al.(2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation.

Description:
Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 6 (CXCR6) detection. Tested with WB, IHC-P in Mouse, Rat.

Synonyms:
C X C chemokine receptor type 6 antibody, C-X-C chemokine receptor type 6 antibody, CD 186 antibody, CD186 antibody, CD186 antigen antibody, CDw186 antibody, Chemokine(C X C motif) receptor 6 antibody, Chemokine C X C motif receptor 6 antibody, Chemokine C-X-C Motif Receptor 6 antibody, Chemokine CXC motif receptor 6 antibody, Chemokine receptor 6 antibody, CXC chemokine receptor type 6 antibody, CXC R6 antibody, CXC-R6 antibody, CXCR 6 antibody, CXCR-6 antibody, CXCR6 antibody, CXCR6_HUMAN antibody, G protein coupled receptor antibody, G protein coupled receptor bonzo antibody, G protein coupled receptor STRL 33 antibody, G protein coupled receptor STRL33 antibody, G protein coupled receptor TYMSTR antibody, G-protein coupled receptor bonzo antibody, G-protein coupled receptor STRL33 antibody, STRL 33 antibody, STRL33 antibody, TYMSTR antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bonzo(331-351aa EDSSKTCSASHNVETTSMFQL), different from the related rat sequence by two amino acids, and from the related human sequence by three amino acidsA synthetic peptide corresponding to a sequence at the C-terminus of mouse Bonzo(331-351aa EDSSKTCSASHNVETTSMFQL), different from the related rat sequence by two amino acids, and from the related human sequence by three amino acids

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.