CD192 Polyclonal Antibody

Background:
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.

Research Area: Cancer, Cardiovascular, Immunology, Microbiology, Signal Transduction

Synonyms:
C C chemokine receptor type 2, C C CKR 2, C-C chemokine receptor type 2, C-C CKR-2, CC chemokine receptor type 2, CC CKR 2, CC-CKR-2, CCCKR2, CCR 2, CCR-2, CCR1L, CCR2, CCR2, CCR2A, CCR2B, CCR5L, CD192, CD192 antigen, Chemokine C C motif receptor 2, Chemokine CC Motif Receptor 2, CKR 2, CKR2, CKR2A, CKR2B, CMKBR2, MCP 1 R, MCP-1-R, MCP1 RECEPTOR, MCP1R, Monocyte chemoattractant protein 1 receptor, Monocyte Chemotactic Protein 1 Receptor, Monocyte Chemotactic Protein 1 Receptor

Immunogen: Synthetic peptide of human CCR2

Swissprot: P41597
Gene Accession: NP_001116513

Calculated MW: 42 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.