CD194 (CCR4) polyclonal, anti-mouse, rat

Quantity: 100 µg

Background:
CCR4,C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194(cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines. The CCR4 gene is mapped to chromosome 3. Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Description:
Rabbit IgG polyclonal antibody for C-C chemokine receptor type 4 (CCR4) detection. Tested with WB in Mouse, Rat.

Synonyms:
C-C chemokine receptor type 4 antibody, C C CKR 4 antibody, C-C chemokine receptor type 4 antibody, C-C CKR-4 antibody, CC CKR 4 antibody, CC-CKR-4 antibody, CCR 4 antibody, CCR-4 antibody, CCR4 antibody, CCR4_HUMAN antibody, CD194 antibody, Chemokine(CC motif) receptor 4 antibody, chemokine C C motif receptor 4 antibody, ChemR13 antibody, CKR4 antibody, CMKBR 4 antibody, CMKBR4 antibody, HGCN 14099 antibody, K5 5 antibody, K5-5 antibody, MGC88293 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of mouse CCR4(346-360aa, SYTQSTVDHDFRDAL), identical to the related rat sequence.A synthetic peptide corresponding to a sequence in the middle region of mouse CCR4(346-360aa, SYTQSTVDHDFRDAL), identical to the related rat sequence.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.