CD196 (CCR6) polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.

Description:
Rabbit IgG polyclonal antibody for C-C chemokine receptor type 6 (CCR6) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
BN 1 antibody, BN1 antibody, C C chemokine receptor type 6 antibody, C C CKR 6 antibody, C-C chemokine receptor type 6 antibody, C-C CKR-6 antibody, CC chemokine receptor type 6 antibody, CC CKR 6 antibody, CC R6 antibody, CC-CKR-6 antibody, CCCKR6 antibody, CCR 6 antibody, CCR-6 antibody, Ccr6 antibody, CCR6_HUMAN antibody, CD 196 antibody, CD196 antibody, CD196 antigen antibody, Chemokine(C C motif) receptor 6 antibody, Chemokine(C C) receptor 6 antibody, Chemokine(CC motif) receptor 6 antibody, Chemokine(CC) receptor 6 antibody, Chemokine receptor 6 antibody, Chemokine receptor like 3 antibody, Chemokine receptor-like 3 antibody, CKR 6 antibody, CKR L3 antibody, CKR-L3 antibody, CKR6 antibody, CKRL3 antibody, CMKBR6 antibody, CMKBR6 antibody, DCR 2 antibody, DCR2 antibody, DRY 6 antibody, DRY6 antibody, G protein coupled receptor 29 antibody, G-protein coupled receptor 29 antibody, GPR 29 antibody, GPR CY4 antibody, GPR-CY4 antibody, GPR29 antibody, GPRCY 4 antibody, GPRCY4 antibody, LARC receptor antibody, Seven transmembrane receptor lymphocyte 22 antibody, STRL 22 antibody, STRL22 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6(358-374aa RQTSETADNDNASSFTM), different from the related rat and mouse sequences by two amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6(358-374aa RQTSETADNDNASSFTM), different from the related rat and mouse sequences by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.