CD1A antibody (clone M1-2-1B5), anti-human
€435.00
In stock
SKU
AC-AT1432a
Catalog Number: AC-AT1432a
Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB, E
Request Information AC-AT1432a">Request Information
Background:
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
Other Names:
T-cell surface glycoprotein CD1a, T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen, CD1a, CD1A
Antigen Type:
Recombinant Protein
Gene Name: CD1A
Gene ID: 909
NCBI Accession: NP_001754.2
Primary Accession: P06126
Other Accession: BC031645
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
Other Names:
T-cell surface glycoprotein CD1a, T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen, CD1a, CD1A
Antigen Type:
Recombinant Protein
Gene Name: CD1A
Gene ID: 909
NCBI Accession: NP_001754.2
Primary Accession: P06126
Other Accession: BC031645
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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