CD1B polyclonal (N-term), anti-human

CD1B polyclonal (N-term), anti-human

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In stock
SKU
AC-AP18475a
Catalog Number: AC-AP18475a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36689
Applications: WB
Datasheet

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Background:
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq].

Other Names:
T-cell surface glycoprotein CD1b, CD1b, CD1B

Target/Specificity:
This CD1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-85 amino acids from the N-terminal region of human CD1B.

Antigen Region:
57-85

Antigen Type: Synthetic Peptide

Gene Name: CD1B
Gene ID: 910
Primary Accession: P29016
NCBI Accession: NP_001755.1
Other Accession: NP_001755.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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