CD1C Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13430b
Background:
This gene encodes a member of the CD1 family oftransmembrane glycoproteins, which are structurally related to themajor histocompatibility complex (MHC) proteins and formheterodimers with beta-2-microglobulin. The CD1 proteins mediatethe presentation of primarily lipid and glycolipid antigens of selfor microbial origin to T cells. The human genome contains five CD1family genes organized in a cluster on chromosome 1. The CD1 familymembers are thought to differ in their cellular localization andspecificity for particular lipid ligands. The protein encoded bythis gene is broadly distributed throughout the endocytic systemvia a tyrosine-based motif in the cytoplasmic tail. Alternativelyspliced transcript variants of this gene have been observed, buttheir full-length nature is not known.
Other Names:
T-cell surface glycoprotein CD1c, CD1c, CD1C
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13430b was selected from the C-term region of CD1C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CD1C
Gene ID: 911
Primary Accession: P29017
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the CD1 family oftransmembrane glycoproteins, which are structurally related to themajor histocompatibility complex (MHC) proteins and formheterodimers with beta-2-microglobulin. The CD1 proteins mediatethe presentation of primarily lipid and glycolipid antigens of selfor microbial origin to T cells. The human genome contains five CD1family genes organized in a cluster on chromosome 1. The CD1 familymembers are thought to differ in their cellular localization andspecificity for particular lipid ligands. The protein encoded bythis gene is broadly distributed throughout the endocytic systemvia a tyrosine-based motif in the cytoplasmic tail. Alternativelyspliced transcript variants of this gene have been observed, buttheir full-length nature is not known.
Other Names:
T-cell surface glycoprotein CD1c, CD1c, CD1C
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13430b was selected from the C-term region of CD1C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CD1C
Gene ID: 911
Primary Accession: P29017
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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