CD1e polyclonal, anti-human, mouse, rat antibody
€220.00
In stock
SKU
AC-ABV11446-50
Catalog Number: AC-ABV11446-50
Size: 50 µl
Host: Rabbit IgG
Applications: WB, IF, ICC
Datasheet
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Size: 50 µl
Host: Rabbit IgG
Applications: WB, IF, ICC
Datasheet
Request Information
Background:
CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.
Other Names:
T-cell surface glycoprotein CD1e membrane-associated, hCD1e, R2G1, CD1e
Primary Accession: P15812
Gene Name: CD1E
Gene ID: 913
Concentration (mg/ml): 1 mg/ml
CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.
Other Names:
T-cell surface glycoprotein CD1e membrane-associated, hCD1e, R2G1, CD1e
Primary Accession: P15812
Gene Name: CD1E
Gene ID: 913
Concentration (mg/ml): 1 mg/ml
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