CD20 polyclonal, anti-human

Quantity: 100 µg

Background:
CD20, also known as MS4A1, is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. It is mapped to 11q12.2. This gene encodes a member of the membrane-spanning 4A gene family. The function of CD20 is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that CD20 acts as a calcium channel in the cell membrane. What’s more, this protein may be involved in the regulation of B-cell activation and proliferation.

Description:
Rabbit IgG polyclonal antibody for B-lymphocyte antigen CD20 (MS4A1) detection. Tested with WB, IHC-P in Human.

Synonyms:
APY antibody, ATOPY antibody, B lymphocyte antigen CD20 antibody, B Lymphocyte Cell Surface Antigen B1 antibody, B-lymphocyte antigen CD20 antibody, B-lymphocyte cell-surface antigen B1 antibody, B-lymphocyte surface antigen B1 antibody, B1 antibody, Bp 35 antibody, Bp35 antibody, CD 20 antibody, CD20 antibody, CD20 antigen antibody, CD20 receptor antibody, CD20_HUMAN antibody, Fc epsilon receptor I beta chain antibody, Fc Fragment of IgE high affinity I receptor for beta polypeptide antibody, FCER1B antibody, FCERI antibody, High affinity immunoglobulin epsilon receptor subunit beta antibody, IgE Fc receptor subunit beta antibody, IGEL antibody, IGER antibody, IGHER antibody, LEU16 antibody, LEU16 antibody, leukocyte surface antigen Leu 16 antibody, Leukocyte surface antigen Leu-16 antibody, Ly44 antibody, Membrane spanning 4 domains subfamily A member 2 antibody, Membrane-spanning 4-domains subfamily A member 1 antibody, MS4A1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD20 recombinant protein (Position: M1-D261). Human CD20 shares 75% amino acid (aa) sequence identity with mouse CD20.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.