CD206 Polyclonal Antibody

Background:
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.

Research Area: Cancer, Immunology

Synonyms:
bA541I19.1, C type lectin domain family 13 member D, C-type lectin domain family 13 member D, CD 206, CD206, CD206 antigen, CLEC13D, CLEC13DL, Macrophage mannose receptor 1, Macrophage mannose receptor 1 like protein 1, Macrophage mannose receptor, Mannose receptor C type 1, Mannose receptor C type 1 like 1, MMR, MRC 1, MRC1, MRC1, MRC1L1, OTTHUMP00000045206

Immunogen: Synthesized peptide derived from the Internal region of human CD206.

Swissprot: P22897

Calculated MW: 166 kDa
Observed MW: 170 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://pubmed.ncbi.nlm.nih.gov/31185006/