CD21 polyclonal, anti-human
€428.00
In stock
SKU
BS90225
Catalog Number: BS90225
Size: 100 µl
Other Size: 50 µl
Isotype: rabbit IgG
Applications: ICC, IHC, FC
Questions? Contact us!
Size: 100 µl
Other Size: 50 µl
Isotype: rabbit IgG
Applications: ICC, IHC, FC
Questions? Contact us!
Background:
CD21 (also known as complement receptor (CR) type 2) is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. CD21 is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigens.
Alternative Name:
Cr2, EBV receptor, CR2, C3DR, C3DR, CD 21, CD21, Complement C3d receptor 2, Complement C3d receptor, Complement component (3d/Epstein Barr virus) receptor 2, Complement receptor type 2, CR, Cr2, CR2, CVID7, EBV receptor, EBV-R, Epstein Barr virus receptor, Epstein-Barr virus receptor, EVBR, SLEB9,
Application Dilution:
IHC:1:50-1:200
ICC:1:50-1:200
FC:1:50-1:100
Specificity: CD21 polyclonal antibody detects endogenous levels of CD21 protein.
Immunogen:
Peptide.
Swiss-Prot: P20023(Human)
Purification & Purity:
Peptide affinity purified.
Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
For research use only, not for use in diagnostic procedure.
CD21 (also known as complement receptor (CR) type 2) is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. CD21 is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigens.
Alternative Name:
Cr2, EBV receptor, CR2, C3DR, C3DR, CD 21, CD21, Complement C3d receptor 2, Complement C3d receptor, Complement component (3d/Epstein Barr virus) receptor 2, Complement receptor type 2, CR, Cr2, CR2, CVID7, EBV receptor, EBV-R, Epstein Barr virus receptor, Epstein-Barr virus receptor, EVBR, SLEB9,
Application Dilution:
IHC:1:50-1:200
ICC:1:50-1:200
FC:1:50-1:100
Specificity: CD21 polyclonal antibody detects endogenous levels of CD21 protein.
Immunogen:
Peptide.
Swiss-Prot: P20023(Human)
Purification & Purity:
Peptide affinity purified.
Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
For research use only, not for use in diagnostic procedure.
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