CD225 (IFITM1) polyclonal, anti-human

Quantity: 100 µg

Background:
Interferon-induced Transmembrane Protein 1(IFITM1), also called Interferon-induced Protein 17(IFI17). IFITM1 activity is required for primordial germ cells(PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins(Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17-kDa proteins to inhibit cell growth.

Description:
Rabbit IgG polyclonal antibody for Interferon-induced transmembrane protein 1 (IFITM1) detection. Tested with WB, IHC-P, IHC-F in Human.

Synonyms:
9-27 antibody, CD 225 antibody, CD 225 antigen antibody, CD225 antibody, CD225 antigen antibody, Dispanin subfamily A member 2a antibody, DSPA2a antibody, IFI 17 antibody, IFI17 antibody, IFITM1 antibody, IFM1_HUMAN antibody, Interferon induced protein 17 antibody, interferon induced transmembrane protein 1(9-27) antibody, Interferon induced transmembrane protein 1 antibody, Interferon inducible protein 9-27 antibody, Interferon-induced protein 17 antibody, Interferon-induced transmembrane protein 1 antibody, Interferon-inducible protein 9-27 antibody, Leu 13 antibody, Leu 13 antigen antibody, Leu-13 antigen antibody, LEU13 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human IFITM1(1-17aa MHKEEHEVAVLGPPPST).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.