CD227 (MUC-1) (clone 139H2), anti-human
€564.00
In stock
SKU
ARP-21-5212
Catalog Number: 21-5212
Size: 100 µg
Isotype: Mouse IgG1
Size: 100 µg
Isotype: Mouse IgG1
Background:
Mucin 1, cell surface associated (MUC-1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in Humans. MUC-1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs.The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity.Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with colon, breast, ovarian, lung and pancreatic cancers.
Clone: 139H2
Isotype: Mouse IgG1
Source: The 139H2 monoclonal antibody is derived by immunisation of Balb/c mice with Human milk-fat globule membranes (HMFGM).
Reactivity: human
Specificity: Mouse monoclonal antibody has been raised anti Human milk-fat globule membranes (HMFGM) to obtain reagents for mammary tumor diagnosis. This monoclonal reacts towards an peptide epitope in the repeat region of MUC-1.
Form: Each vial contains 100ul purified monoclonal antibody in PBS containing 0.09% sodium azide.
Applications: Electron microscopy, ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry (frozen), Immunoprecipitation, Western blotting
Storage: Store at 4C, or in small aliquots at -20C.
Mucin 1, cell surface associated (MUC-1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in Humans. MUC-1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs.The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity.Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with colon, breast, ovarian, lung and pancreatic cancers.
Clone: 139H2
Isotype: Mouse IgG1
Source: The 139H2 monoclonal antibody is derived by immunisation of Balb/c mice with Human milk-fat globule membranes (HMFGM).
Reactivity: human
Specificity: Mouse monoclonal antibody has been raised anti Human milk-fat globule membranes (HMFGM) to obtain reagents for mammary tumor diagnosis. This monoclonal reacts towards an peptide epitope in the repeat region of MUC-1.
Form: Each vial contains 100ul purified monoclonal antibody in PBS containing 0.09% sodium azide.
Applications: Electron microscopy, ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry (frozen), Immunoprecipitation, Western blotting
Storage: Store at 4C, or in small aliquots at -20C.
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