CD23 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.

Description:
Rabbit IgG polyclonal antibody for Low affinity immunoglobulin epsilon Fc receptor (FCER2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Blast 2 antibody, BLAST-2 antibody, Blast2 antibody, C type lectin domain family 4 member J antibody, C-type lectin domain family 4 member J antibody, C-type lectin domain family 4, member J antibody, CD 23 antibody, CD 23A antibody, CD23 antibody, CD23 antigen antibody, CD23A antibody, CLEC 4J antibody, CLEC4J antibody, Fc epsilon RII antibody, Fc fragment of IgE low affinity II receptor for antibody, Fc fragment of IgE, low affinity II, receptor for (CD23) antibody, Fc of IgE, low affinity II, receptor for (CD23) antibody, Fc receptor IgE low affinity II alpha polypeptide antibody, Fc receptor, IgE, low affinity II, alpha polypeptide, isoform CRA_a antibody, Fc-epsilon-RII antibody, FCE 2 antibody, FCE2 antibody, FCER 2 antibody, Fcer2 antibody, FCER2_HUMAN antibody, FCER2A antibody, FceRII antibody, IgE binding factor antibody, IgE receptor lymphocyte antibody, IgE-binding factor antibody, IGEBF antibody, Immunoglobulin E binding factor antibody, Immunoglobulin E receptor, low affinity II antibody, Immunoglobulin E-binding factor antibody, LEUKOCYTE ANTIGEN CD23 antibody, Low Affinity IgE Receptor antibody, Low affinity immunoglobulin epsilon Fc receptor antibody, Low affinity immunoglobulin epsilon Fc receptor membrane bound form antibody, Low affinity immunoglobulin epsilon Fc receptor soluble form antibody, Ly-42 antibody, Ly42 antibody, Lymphocyte antigen CD23 antibody, Lymphocyte IgE receptor antibody, MGC93219 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived mouse CD23 recombinant protein (Position: E50-P331). Mouse CD23 shares 52% amino acid (aa) sequence identity with human CD23.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.