CD239 (clone 8C4E6), anti-human

CD239 (clone 8C4E6), anti-human

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In stock
SKU
BT-MCA2201
Catalog Number: BT-MCA2201
Size(s): 50μL, 100μL
Isotype: Mouse IgG2a
Reactivity: human
Application(s): IHC, FCM
Datasheet
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Background:
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Others

Synonyms: BCAM, AU, LU, MSK19

Immunogen: Purified recombinant fragment of human CD239 (AA: extra 32-197) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage
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