CD239 (Lub Antigen, ISBT 5002) (clone BRIC 108) Culture supernatant, anti-human

Decription:
Mouse monoclonal antibody to human Blood Group Lub (ISBT 5002)/CD239 Culture supernatant. The Lutheran (Lu) blood group is also known as B-cell adhesion molecule (B-CAM), Auberger blood group and CD 239. The antigens of the Lu blood group system are carried on two red cell membrane glycoproteins of Mr 85 and 78 kDa1,2,. The Lu antigens and BRIC 108 expression appears to be restricted to red cells in peripheral blood, but they or related molecules are widely expressed in human tissues, are present in large amounts in kidney endothelium, and the glycoprotein is developmentally regulated in human liver5. Lu is a specific adhesive receptor for the extracellular matrix protein human laminin 10/116.

Synonyms: Lutheran b blood group antigen, CD239, B-CAM, Auberger blood group

Clone: BRIC 108

Isotype: Mouse IgG1 kappa light chain

Immunogen: Lub (ISBT 5002)/CD239 antigen was made in response to immunisation with intact human red cells.

Reactivity: human

Form: Culture Supernatant

Applications: Flow Cytometry, Indirect Immunofluorescence, Immunoblotting, Immunocytochemical techniques.

Working Dilution: Optimal dilution should be performed by user

Storage: 2-8C for immediate use, or at -20C (aliquot)

References:
Parsons SF, et al. (1987) Transfusion 27, 61-63
Daniels GL, et al. (1989) Vox Sang. 57, 137-141
Merry AH, et al. (1987) Vox Sang. 53, 57-60
Anstee DJ, et al. (1988) XX Congress of ISBT/BBTS, London p264 (abstract)