CD240CE (Rh E, ISBT 4003) blood group antigen (clone COE) PE, anti-human

Decription:
Human heterohybridoma to human Rh E (ISBT 4003)/CD240CE blood group-related antigen Culture supernatant. Rh is the most complex of the human blood group systems, with 45 well-defined antigens. Rh E (Rh 3 or rh") is an antigen of the Rh blood group system. The Rh antigens are carried on a number of closely related poly­peptides of around Mr 30 0001,. Estimated numbers of E sites on red cells range from 27,500 on CDE/cDE to 17,900 on cDE/cde. 30% of Caucasians are Rh E+ with frequencies of 0.1411 for cDE (R2) and 0.0119 for cdE (r") Rh haplotypes.

Synonyms: Rh E antigen, CD240CE

Clone: COE

Isotype: Human IgM lambda light chain

Immunogen: COE is a direct agglutinin with red cells of all Rh phenotypes possessing the E antigen.

Reactivity: human

Form: PE-conjugate, in PBS buffer, pH 7.2 containing 0.1% sodium azide, 1% BSA

Applications: Flow Cytometry, Indirect Immunofluorescence

Working Dilution: 2ul per test (may change from lot to lot)

Storage: 2-8C, do not freeze

References:
1. Avent, ND., et al. (1990) Biochem J. 271: 821-825
2. Agre, P. & Cartron, JP. (1991), Blood 78: 551 (review)
3. Issitt, PD (1985) Applied Blood Group Serology, 3rd Ed. Montgomery Scientific Publications, Miami, Florida, USA
4. Mollison, PL. (1987) Blood transfusion in Clinical Medicine, 8th Ed. Blackwell Scientific Publications
5. Rouger P Muller JY (eds) (1997) Proceedings of the third International workshop and symposium on monoclonal antibodies against human red cells and related antigens, Nantes 1996