CD25 (IL-2 Receptor) (clone IR2-D4) biotin, anti-mouse
€224.00
In stock
SKU
ARP-06-1046-3
Catalog Number: 06-1046-3
Size: 50 µg
Isotype: Rat IgM
Size: 50 µg
Isotype: Rat IgM
Background:
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency
Decription:
Rat monoclonal Antibody to mouse IL-2 Receptor, Biotin conjugate
Synonyms: CD25, IL2R
Clone: IR2-D4
Isotype: Rat IgM
Immunogen: Con-A activated T-cells
Reactivity: mouse
Specificity: Mouse IL-2 Receptor (b). (Chain specificity was not determined)
Form: Affinity Purified, in PBS containing 0.1% Sodium Azide
Applications: FACS analysis
Working Dilution: For Flow Cytometry use 5-10µl per 106 cells. Analysis was done on Con-A stimulated lymph node T-cells. Dilution of 1:20 will block 80-90% of stimulation of CTLL cells by 100 U of rIL-2.
Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency
Decription:
Rat monoclonal Antibody to mouse IL-2 Receptor, Biotin conjugate
Synonyms: CD25, IL2R
Clone: IR2-D4
Isotype: Rat IgM
Immunogen: Con-A activated T-cells
Reactivity: mouse
Specificity: Mouse IL-2 Receptor (b). (Chain specificity was not determined)
Form: Affinity Purified, in PBS containing 0.1% Sodium Azide
Applications: FACS analysis
Working Dilution: For Flow Cytometry use 5-10µl per 106 cells. Analysis was done on Con-A stimulated lymph node T-cells. Dilution of 1:20 will block 80-90% of stimulation of CTLL cells by 100 U of rIL-2.
Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles
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