CD25 (IL-2 Receptor, IL-2R) (clone NR-72) biotin, anti-human
€224.00
In stock
SKU
ARP-06-1047-3
Catalog Number: 06-1047-3
Size: 50 µg
Isotype: Mouse IgG2a
Size: 50 µg
Isotype: Mouse IgG2a
Background:
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency
Decription:
Mouse monoclonal Antibody to human IL-2 Receptor, Biotin conjugate
Synonyms: CD25, IL2R
Clone: NR-72
Isotype: Mouse IgG2a
Immunogen: Con A-activated human T cells
Reactivity: human
Specificity: Human IL-2 Receptor
Form: Affinity Purified, in PBS containing 0.1% Sodium Azide
Applications: FACS analysis, Sorting
Working Dilution: 1:50 dilution will block 70-80% of CTLL proliferative response to 50 units of r.human IL-2 and will stain 70% of PHA-activated human T cells (by FACS) 10µl will stain 106 IL-2R positive cells for FACS analysis or sorting
Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency
Decription:
Mouse monoclonal Antibody to human IL-2 Receptor, Biotin conjugate
Synonyms: CD25, IL2R
Clone: NR-72
Isotype: Mouse IgG2a
Immunogen: Con A-activated human T cells
Reactivity: human
Specificity: Human IL-2 Receptor
Form: Affinity Purified, in PBS containing 0.1% Sodium Azide
Applications: FACS analysis, Sorting
Working Dilution: 1:50 dilution will block 70-80% of CTLL proliferative response to 50 units of r.human IL-2 and will stain 70% of PHA-activated human T cells (by FACS) 10µl will stain 106 IL-2R positive cells for FACS analysis or sorting
Storage: 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles
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