CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (clone 203.6), anti-human
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In stock
SKU
AC-AH12677
Catalog Number: AC-AH12677
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: 203.6
Applications: IF, FC
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: 203.6
Applications: IF, FC
Datasheet
Request Information
Background:
Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
Other Names:
CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7
Gene Name: CD27 (HGNC:11922)
Gene ID: 939
Primary Accession: P26842
Other Accession: 939, 355307
Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
Other Names:
CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, CD27, CD27, TNFRSF7
Gene Name: CD27 (HGNC:11922)
Gene ID: 939
Primary Accession: P26842
Other Accession: 939, 355307
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