CD271 (p75 NGF Receptor) polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
The Low-Affinity Nerve Growth Factor Receptor(also called the NGFR or p75 neurotrophin receptor) is one of the two receptor types for the neurotrophins, a family of protein growth factors that stimulate neuronal cells to survive and differentiate. It is mapped to 17q21.33. Overexpression of NGFR was also found to activate the SM pathway. NGFR is a receptor for rabies virus, and it is also a coreceptor for the NOGO receptor for MAG signaling. This gene is a signaling partner for EPHAs and the EPHA/NGFR complex reverse signals can mediate axon repulsion required for guidance and mapping. NGFR is involved in activity-dependent synaptic plasticity. It has been shown to interact with PRKACB, FSCN1, TRAF4, Nerve growth factor, TRAF2, NDN, NGFRAP1 and MAGEH1.

Description:
Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 16 (NGFR) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
CD271 antibody, CD271 antigen antibody, Gp80 LNGFR antibody, Gp80-LNGFR antibody, Low affinity nerve growth factor receptor antibody, Low affinity neurotrophin receptor p75NTR antibody, Low affinity neurotrophin receptor p75NTR antibody, Low-affinity nerve growth factor receptor antibody, Nerve growth factor receptor antibody, Nerve growth factor receptor TNFR superfamily member 16 antibody, NGF receptor antibody, NGF receptor antibody, Ngfr antibody, p75 ICD antibody, p75 ICD antibody, p75 Neurotrophin receptor antibody, p75 NTR antibody, p75(NTR) antibody, p75NTR antibody, TNFR Superfamily Member 16 antibody, TNFRSF16 antibody, TNR16_HUMAN antibody, Tumor necrosis factor receptor superfamily member 16 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human p75 NGF Receptor(397-414aa TLDALLAALRRIQRADLV), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse.
Predicted to work with: rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.