CD275 Polyclonal Antibody

Background:
This gene is ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. May be play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.

Research Area: Immunology

Synonyms:
B7 H2, B7 homolog 2, B7 homologue 2, B7 like protein Gl50, B7 related protein 1, B7-H2, B7-like protein Gl50, B7-related protein 1, B7H2, B7RP 1, B7RP-1, B7RP1, CD 275, CD275, CD275 antigen, GL 50, GL50, ICOS L, ICOS LG, ICOS ligand, ICOSL, ICOSL, Icoslg, Inducible T cell co stimulator ligand, KIAA0653, LICOS, Transmembrane protein B7 H2 ICOS ligand

Immunogen: Synthetic peptide of human ICOSLG

Swissprot: O75144
Gene Accession: NP_056074.1

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-14597/sc-14596/sc-25586