CD276 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM8677b
Catalog Number: AC-AM8677b
Size: 50 µl, 200 µl
Isotype: mouse IgG1,κ
Clone Name: 2009CT652.35.9
Applications: WB, IHC-P
Datasheet
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Size: 50 µl, 200 µl
Isotype: mouse IgG1,κ
Clone Name: 2009CT652.35.9
Applications: WB, IHC-P
Datasheet
Request Information
Background:
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Other Names:
CD276 antigen, 4Ig-B7-H3, B7 homolog 3, B7-H3, Costimulatory molecule, CD276, CD276, B7H3
Target/Specificity:
This CD276 antibody is generated from a mouse immunized with a recombinant protein from the human region of human CD276.
Antigen Type: Synthesized Peptide
Gene Name: CD276
Gene ID: 80381
Primary Accession: Q5ZPR3
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Other Names:
CD276 antigen, 4Ig-B7-H3, B7 homolog 3, B7-H3, Costimulatory molecule, CD276, CD276, B7H3
Target/Specificity:
This CD276 antibody is generated from a mouse immunized with a recombinant protein from the human region of human CD276.
Antigen Type: Synthesized Peptide
Gene Name: CD276
Gene ID: 80381
Primary Accession: Q5ZPR3
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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