CD281 (TLR1) polyclonal, anti-human

Quantity: 100 µg

Background:
Toll-like receptor 1(TLR1), also called TIL or CD281 is a member of the Toll-like receptor family(TLR) of pattern recognition receptors of the innate immune system. This gene is mapped to 4p14 by fluorescence in situ hybridization. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns(PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

Description:
Rabbit IgG polyclonal antibody for Toll-like receptor 1 (TLR1) detection. Tested with WB in Human.

Synonyms:
CD281 antibody, CD281 antigen antibody, KIAA0012 antibody, LPRS5 antibody, rsc786 antibody, Similar to Drosophila Toll protein antibody, TIL antibody, TIL. LPRS5 antibody, Tlr1 antibody, TLR1_HUMAN antibody, Toll(Drosophila) homolog antibody, Toll like receptor 1 antibody, Toll like receptor 1 Precursor antibody, Toll-like receptor 1 antibody, Toll/Interleukin 1 receptor like antibody, Toll/Interleukin 1 receptor-like antibody, Toll/interleukin-1 receptor-like protein antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human TLR1(771-786aa NLRAAINIKLTEQAKK).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.