CD285 (TLR5) polyclonal, anti-human

Quantity: 100 µg

Background:
TLR5 encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.

Description:
Rabbit IgG polyclonal antibody for Toll-like receptor 5 (TLR5) detection. Tested with WB, IHC-P in Human.

Synonyms:
FLJ10052 antibody, MGC126430 antibody, MGC126431 antibody, SLEB1 antibody, TIL 3 antibody, TIL3 antibody, TLR 5 antibody, Tlr5 antibody, TLR5_HUMAN antibody, Toll like receptor 5 antibody, Toll like receptor 5 precursor antibody, Toll-like receptor 5 antibody, Toll/interleukin 1 receptor like protein 3 antibody, Toll/interleukin-1 receptor-like protein 3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human TLR5 (801-828aa MKHQSIRGFVQKQQYLRWPEDFQDVGWF), different from the related mouse sequence by five amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.