CD29 (Beta-1 Integrin) polyclonal, anti-human, mouse, rat, bovine, horse, pig, sheep, dog, rabbit, chicken

Protein Family: Cell Adhesion Molecules, Cellular Antigens, CAM Ligands

Pathway and Disease: Cancers, Cell Growth and Death, Cell Motility, Immune System, Infectious Diseases

Description:
Beta-1 Integrin is a receptor for collagen, where it binds the proline-hydroxylated sequence G-F-P-G-E-R. Beta-1 integrin associates with alpha-1, alpha-2, alpha-3, alpha-4, alpha-5, alpha-6, alpha-7, alpha-8, alpha-9, alpha-10, alpha-11 or alpha-V. In HIV-1 infection, the interaction of beta-1 integrin with extracellular viral Tat protein enhances angiogenesis in Kaposi's sarcoma lesions.

Alternate Names: Integrin beta-1, Integrin β1, Integrin-β1, Fibronectin receptor subunit beta, Integrin VLA-4 subunit beta, CD29, ITGB1, FNRB

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P05556

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Beta-1 integrin.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.