CD2AP Picoband™ (clone 5F8), anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO14802
Catalog Number: AC-ABO14802
Size: 100 µg
Isotype: Mouse
Applications: WB, IHC, IF, ICC, FC
Datasheet
Request Information
Size: 100 µg
Isotype: Mouse
Applications: WB, IHC, IF, ICC, FC
Datasheet
Request Information
Description: Anti-CD2AP Antibody Picoband™ (monoclonal, 5F8) . Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T- cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
Other Names: CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP
Clone Name(s):
Clone: 5F8
Subcellular Localization: Cytoplasm, cytoskeleton. Cell projection, ruffle. Colocalizes with F-actin and BCAR1/p130Cas in membrane ruffles. Located at podocyte slit diaphragm between podocyte foot processes (By similarity). During late anaphase and telophase, concentrates in the vicinity of the midzone microtubules and in the midbody in late telophase.
Tissue Specificity: Widely expressed in fetal and adult tissues.
Gene ID: 23607
Immunogen: E. coli-derived human CD2AP recombinant protein (Position: K253-K337).
Calculated MW: 71451
Format: Lyophilized
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Protein Function:
Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T- cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
Other Names: CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP
Clone Name(s):
Clone: 5F8
Subcellular Localization: Cytoplasm, cytoskeleton. Cell projection, ruffle. Colocalizes with F-actin and BCAR1/p130Cas in membrane ruffles. Located at podocyte slit diaphragm between podocyte foot processes (By similarity). During late anaphase and telophase, concentrates in the vicinity of the midzone microtubules and in the midbody in late telophase.
Tissue Specificity: Widely expressed in fetal and adult tissues.
Gene ID: 23607
Immunogen: E. coli-derived human CD2AP recombinant protein (Position: K253-K337).
Calculated MW: 71451
Format: Lyophilized
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
| Is Featured? | No |
|---|
Write Your Own Review