CD2AP polyclonal, anti-human

Background:
Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (PubMed:10339567). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation (By similarity). May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell (By similarity).

Synonyms: CD2AP, CD2-associated protein, Adapter protein CMS, CMS,

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human CD2AP

Gene Symbol: CD2AP

Gene ID: 23607

Swiss prot: Q9Y5K6

Calculated MW: 71kDa

Recommended dilution:
WB 1:5000-8000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.