CD2BP2 Polyclonal Antibody

Background:
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Research Area: Immunology

Synonyms:
CD2BP2, FWP010, LIN1, PPP1R59, Snu40, U5-52K

Immunogen: Recombinant fusion protein of human CD2BP2 (NP_006101.1).

Swissprot: O95400
Gene ID: 10421

Calculated MW: 37 kDa
Observed MW: 54 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.