CD3 epsilon polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11. It is mapped to 11q23.3. The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.

Description:
Rabbit IgG polyclonal antibody for T-cell surface glycoprotein CD3 epsilon chain (CD3E) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.

Synonyms:
CD3 epsilon antibody, CD3e antibody, CD3E antibody, CD3e antigen epsilon polypeptide (TiT3 complex) antibody, CD3E antigen epsilon polypeptide antibody, CD3E antigen, epsilon subunit antibody, CD3e molecule epsilon antibody, CD3e molecule, epsilon (CD3 TCR complex) antibody, CD3e molecule, epsilon (CD3-TCR complex) antibody, CD3E_HUMAN antibody, IMD18 antibody, T cell antigen receptor complex epsilon subunit of T3 antibody, T cell surface antigen T3/Leu 4 epsilon chain antibody, T cell surface glycoprotein CD3 epsilon chain antibody, T-cell surface antigen T3/Leu-4 epsilon chain antibody, T-cell surface glycoprotein CD3 epsilon chain antibody, T3E antibody, TCRE antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD3 epsilon recombinant protein (Position: D23-I207). Human CD3 epsilon shares 65% amino acid (aa) sequence identity with mouse CD3 epsilon.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, IHC-F, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.