CD30 polyclonal, anti-human

Quantity: 100 µg

Background:
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. This gene is mapped to 1p36.22. CD30 is expressed in embryonal carcinoma but not in seminoma and is thus a useful marker in distinguishing between these germ cell tumors. CD30 mast cell activation represents an IgE-independent activation pathway, which is important for understanding cutaneous inflammation associated with mast cells. In addition to those, CD30 is also associated with anaplastic large cell lymphoma.

Description:
Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 8 (TNFRSF8) detection. Tested with WB in Human.

Synonyms:
CD30 antibody, CD153 antibody, CD30 antibody, CD30 antigen antibody, CD30L receptor antibody, Cytokine receptor CD30 antibody, D1S166E antibody, KI 1 antibody, Ki 1 antigen antibody, Ki-1 antigen antibody, KI1 antibody, Lymphocyte activation antigen CD30 antibody, TNFRSF 8 antibody, TNFRSF8 antibody, TNR8_HUMAN antibody, Tumor Necrosis Factor Receptor Superfamily Member 8 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD30 recombinant protein (Position: T322-K595). Human CD30 shares 60% and 57% amino acid (aa) sequences identity with mouse and rat CD30, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.