CD300b rabbit polyclonal, anti-human, mouse, rat

Backgroud: CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).[supplied by OMIM, Mar 2008],function:Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitement of GRB2.,PTM:Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with TYROBP, which enhances cell surface expression and activation properties. Interacts with GRB2 in the presence of FYN.,tissue specificity:Expressed exclusively in myeloid lineages.,

Synonyms: CMRF35-like molecule 7 (CLM-7, CD300 antigen-like family member B, CMRF35-A2, Immune receptor expressed on myeloid cells 3, IREM-3, Leukocyte mono-Ig-like receptor 5, Triggering receptor expressed on myeloid cells 5, TREM-5, CD antigen CD300b)

Gene Name: CD300LB CD300B CLM7 CMRF35A2 IREM3 LMIR5 TREM5 UNQ2530/PRO6029

Gene ID: 124599

SwissProt ID: A8K4G0

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.