CD304 (Neuropilin 1) polyclonal, anti-human, rat

Quantity: 100 µg

Background:
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Description:
Rabbit IgG polyclonal antibody for Neuropilin-1 (NRP1) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
A5 protein antibody, BDCA4 antibody, BLOOD DENDRITIC CELL ANTIGEN 4 antibody, CD 304 antibody, CD304 antibody, DKFZp686A03134 antibody, DKFZp781F1414 antibody, Neuropilin-1 antibody, Neuropilin1 antibody, Neuropilin1 transmembrane receptor antibody, NP1 antibody, NPN1 antibody, NRP 1 antibody, NRP antibody, NRP1 antibody, NRP1_HUMAN antibody, Vascular endothelial cell growth factor 165 receptor antibody, VEGF165R antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Neuropilin 1 recombinant protein (Position: K504-T827). Human Neuropilin 1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Neuropilin 1, respectively.E.coli-derived human Neuropilin 1 recombinant protein (Position: K504-T827). Human Neuropilin 1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Neuropilin 1, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.