CD309 (VEGFR2) (clone KDR-1), anti-human

Background:
VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues.

Decription:
Mouse IgG monoclonal antibody for VEGFR2, kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR) detection. Tested with IHC-F in Human. No cross reactivity with other proteins.

Synonyms: CD309, VEGFR, FLK1, VEGFR2, TYROSINE KINASE GROWTH FACTOR RECEPTOR, FLK1, MOUSE, HOMOLOG OF, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1

Clone: KDR-1

Isotype: Mouse IgG1

Immunogen: Recombinant human extracellular domain of VEGFR-2(KDR).

Reactivity: human

Form: Lyophilized; Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Applications: IHC-F

Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.