CD314 (NKG2D) (clone 1D11) PURE, anti-human RUO
€270.00
In stock
SKU
IS-314PU-01MG
Introduction:
This activating receptor binds strongly to several ligands including MICA and MICB and ULBP-1, -2, and -3 proteins that are expressed by different target cell types. CD314 functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells. Importantly, CD314 can complement the role of NCR in tumor cell lysis. Remarkably, the combined maskings of NCR and CD314 can reportedly lead to a complete inhibition of NK-mediated lysis of all tumor or normal cells
Application: FCM
Molecular Weight: 25kDa
Storage Temperature: Store in the dark at 2-8 °C
Shelf life: Each reagent is stable until the expiration date shown on the bottle label when stored as directed (at least, one year)
This activating receptor binds strongly to several ligands including MICA and MICB and ULBP-1, -2, and -3 proteins that are expressed by different target cell types. CD314 functions as a triggering receptor involved in natural cytotoxicity mediated by normal NK cells against a variety of tumors or normal target cells. Importantly, CD314 can complement the role of NCR in tumor cell lysis. Remarkably, the combined maskings of NCR and CD314 can reportedly lead to a complete inhibition of NK-mediated lysis of all tumor or normal cells
Application: FCM
Molecular Weight: 25kDa
Storage Temperature: Store in the dark at 2-8 °C
Shelf life: Each reagent is stable until the expiration date shown on the bottle label when stored as directed (at least, one year)
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