CD325 (N-Cadherin) polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
N-cadherin(NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-, and R-cadherin and liver cell adhesion molecule(L-CAM). N-Cadherin,, also known as Cadherin-2, encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96% identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene(including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesis.

Description:
Rabbit IgG polyclonal antibody for Cadherin-2 (CDH2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
CADH2_HUMAN antibody, Cadherin 2 antibody, Cadherin 2 N cadherin neuronal antibody, Cadherin 2 type 1 antibody, Cadherin 2 type 1 N cadherin neuronal antibody, cadherin 2 type 1 N-cadherin neuronal antibody, Cadherin 2, type 1, N-cadherin(neuronal) antibody, Cadherin-2 antibody, Cadherin2 antibody, Calcium dependent adhesion protein neuronal antibody, CD325 antibody, CD325 antigen antibody, CDH2 antibody, CDHN antibody, CDw325 antibody, CDw325 antigen antibody, N cadherin 1 antibody, N-cadherin antibody, NCAD antibody, Neural Cadherin antibody, OTTHUMP00000066304 antibody, OTTHUMP00000067378 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human N Cadherin(701-714aa CQCDSNGDCTDVDR), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence in the middle region of human N Cadherin(701-714aa CQCDSNGDCTDVDR), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.