CD333 (FGFR3) polyclonal, anti-human, mouse, rat, pig, rabbit, guinea pig

Protein Family: Cell Adhesion Molecules, Cellular Antigens, Protein Kinases, Receptors and Channels

Pathway and Disease: Signaling Molecules and Interaction, Signal Transduction, Cancers, Cell Motility

Description:
Fibroblast growth factor receptor 3 (FGFR3 or CD333) is a receptor for acidic and basic fibroblast growth factors, preferentially binding FGF1. FGFR3 is expressed in brain, kidney and testis, with very low or no expression in spleen, heart, and muscle. Defects in FGFR3 can result in a number of diseases and abnormalities, ranging from dwarfism to cancers.

Alternate Names: FGFR3, CD333, FGFR-3, Fibroblast growth factor receptor 3, JTK4

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P22607

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FGFR3.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A and immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.