CD339 (Jagged-1) (clone J1G53-3), anti-human
€204.00
In stock
SKU
ARP-23-A0049
Catalog Number: 23-A0049
Size: 25 µg
Isotype: Mouse IgG1 kappa
Size: 25 µg
Isotype: Mouse IgG1 kappa
Decription:
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
Synonyms: Protein Jagged-1, CD339, JAG1
Clone: J1G53-3
Isotype: Mouse IgG1 kappa
Immunogen: Recombinant human Jagged-1.
Reactivity: human
Specificity: Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct or indirect: 1:500-1:5'000)
Flow Cytometry: (1:20-1:100)
Immunohistochemistry: (paraffin sections)
Western blot: (1:500-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
Synonyms: Protein Jagged-1, CD339, JAG1
Clone: J1G53-3
Isotype: Mouse IgG1 kappa
Immunogen: Recombinant human Jagged-1.
Reactivity: human
Specificity: Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot.
Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Applications:
ELISA: (direct or indirect: 1:500-1:5'000)
Flow Cytometry: (1:20-1:100)
Immunohistochemistry: (paraffin sections)
Western blot: (1:500-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature).
Working Dilution: Optimal conditions must be determined individually for each application.
Concentration: 1mg/ml
Storage: 2-8C immediate use, or -20C (aliquote)
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