CD34 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 KD.CD34 is expressed in humans in hematopoietic stem cells, vascular endothelium, and blasts from 30% of patients with acute myeloid and lymphocytic leukemia. The human CD34 gene spans 26 kb and has 8 exons, a structure quite similar to that of the murine gene. By Southern blot analysis of DNA from a panel of human x mouse somatic cell hybrids using a CD34 cDNA probe demonstrate that the gene for CD34 is located on human chromosome 1 in the 1q12----qter region. CD34 plays an important role in the formation of progenitor cells during both embryonic and adult hematopoiesis.

Description:
Rabbit IgG polyclonal antibody for Hematopoietic progenitor cell antigen CD34 (CD34) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.

Synonyms:
CD34 antibody, Cd34 antibody, CD34 antigen antibody, CD34 molecule antibody, CD34_HUMAN antibody, Cluster designation 34 antibody, Hematopoietic progenitor cell antigen CD34 antibody, HPCA1 antibody, Mucosialin antibody, OTTHUMP00000034733 antibody, OTTHUMP00000034734 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human CD34(366-382aa QATSRNGHSARQHVVAD), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.