CD344 (clone 2F3A7), anti-human

Background:
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

Research Area: Others

Synonyms: FZD4, Fz4, EVR1, FEVR, Fz-4, FzE4, GPCR, hFz4, FZD4S

Immunogen: Purified recombinant fragment of human CD344 (AA: extra 37-222) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage