CD35 / CR1 (Follicular Dendritic Cell Marker) (clone SPM554 ), anti-human, baboon, rhesus, cynomolgus
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In stock
SKU
AC-AH10415
Catalog Number: AC-AH10415
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM554
Applications: IHC-P, IF, FC
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM554
Applications: IHC-P, IF, FC
Datasheet
Request Information
Background:
Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.ĀFollicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
Other Names:
Complement receptor type 1, C3b/C4b receptor, CD35, CR1, C3BR
Gene Name: CR1
Gene ID: 1378
Primary Accession: P17927
Other Accession: 1378, 334019
Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein.ĀFollicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
Other Names:
Complement receptor type 1, C3b/C4b receptor, CD35, CR1, C3BR
Gene Name: CR1
Gene ID: 1378
Primary Accession: P17927
Other Accession: 1378, 334019
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