CD357 (GITR, Tnfrsf18) (clone AIT 158D), anti-human

Decription:
GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.

Synonyms: Tumor Necrosis Factor Receptor Superfamily Member 18, Activation-inducible TNFR Family Receptor, Glucocorticoid-induced TNFR-related Protein, CD357, TNFRSF18, AITR

Clone: AIT 158D

Isotype: Rat IgG2a kappa

Immunogen: Recombinant human GITR.

Reactivity: human

Specificity: Recognizes human GITR. Does not cross-react with mouse GITR.

Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Applications:
ELISA: (direct and indirect: 1:5'000-1:10'000)
Flow Cytometry: (1:1'000)

Working Dilution: Optimal conditions must be determined individually for each application.

Concentration: 1mg/ml

Storage: 2-8C immediate use, or -20C (aliquote)