CD3609 (VEGFR2) polyclonal, anti-human, mouse, rat, guinea pig, hamster, bovine, sheep, dog, chimpanzee, monkey, horse, rabbit, zebrafish, Other

Protein Family: Cellular Antigens, Enzymes, Protein Kinases, Receptors and Channels

Pathway and Disease: Cancers, Cell Communication, Infectious Diseases, Signal Transduction, Signaling Molecules and Interaction

Description:
VEGFR-2 (Vascular endothelial growth factor receptor 2) is a tyrosine-protein kinase and receptor for VEGF or VEGFC. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In HIV-1 infection cases, VEGFR2 interaction with extracellular viral Tat protein enhances angiogenesis in Kaposi's sarcoma lesions.

Alternate Names: Vascular endothelial growth factor receptor 2, VEGFR-2, Protein-tyrosine kinase receptor Flk-1, Kinase insert domain receptor, CD309, KDR, FLK1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500

Accession No.: P35968

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human VEGFR2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
Prokosch V. et al. 2010. Experimental Eye Research. 92(20); 128-137. PMID# 21147101.