CD38 Polyclonal Antibody

CD38 Polyclonal Antibody

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In stock
SKU
ELK-ES4122
Catalog Number: ELK-ES4122
Reactivity: Human
Applications: WB, IHC-p, ELISA
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Background:
CD38 molecule(CD38) Homo sapiens The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Alternative Names:
CD38, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10, CD38

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD38. AA range:211-260

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 35

GeneID: CD38

Storage: -20°C/1 year

NOTE: For Research Use Only
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